HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thionyl Chloride → 2-Acetylthiomethyl-3-phenyl-propionyl chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | HCID 7019602 | HCID 7019602 | — |
| Product | 2-Acetylthiomethyl-3-phenyl-propionyl chloride | HCID 10377734 | — |
Reaction Steps
2.0 g (8.40 mmol) of (R)-2-acetylthiomethyl-3-phenylpropanoic acid (Ia R) (Example 1, stage e) are placed in a round-bottomed flask. The flask is cooled by an ice-water bath and 1.2 g (10.08 mmol) of thionyl chloride are added dropwise. The mixture is stirred overnight to room temperature.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06013829 |
| Source dataset | uspto-grants-2000_01 |
| ORD ID | ord-09377bdea0a4475086783cea02161020 |
| Source note | uspto-grants-2000_01 |