Chlorosuccinimide → HCID 123697877, compound

Participants

Reaction Conditions

Reaction Steps

To a solution of Example 389B (172 mg, 0.60 mmol) in N,N-dimethylformamide (1 mL) was added N-chlorosuccinimide (80 mg, 0.60 mmol). The mixture was heated at 50° C. for 2 hours and purified by reversed phase HPLC (0.1% trifluoroacetic acid(aq):acetonitrile) to afford the title compound with a longer retention time than that of Example 391A.

Provenance & Evidence