Ammonia → HCID 18354614, compound

Participants

Reaction Conditions

Reaction Steps

Methyl 2-t-butyl-4-benzoxazole carboxylate (0.1 g; 0.46mmol) was dissolved in methanol (5 ml), and to this was added aqueous ammonia (5 ml). The mixture was warmed to 40° C. and left to stir for 6 hours at ambient temperature. Once the reaction was complete the solvent was removed under reduced pressure and the product was recrystallised from boiling ethyl acetate and petrol (73%).

Provenance & Evidence