反应详情

Methyl 2-(4-methoxyphenyl)benzoxazole-4-carboxylate was dissolved in liquid ammonia (30 ml) and sealed in an autoclave. The reaction mixture was left at 55° C., 20 bar for >20 hours. Once the reaction was complete the ammonia was removed and the resulting solid recrystallised from boiling ethyl acetate and petrol.

1. customsealed in an autoclave
2. waitThe reaction mixture was left at 55° C.
3. wait20 bar for >20 hours
4. customwas removed
5. customthe resulting solid recrystallised