Acetic Acid → HCID 19366021, compound

Participants

Reaction Conditions

Reaction Steps

To a solution (10 ml) of ethyl 1-(3-cyano-4-(2-ethylbutoxy)phenyl)pyrazole-4-carboxylate (0.88 g) in ethanol was added 2 N aqueous sodium hydroxide solution (1.5 ml) with siring and the mixture was heated at 70° C. for 1 hour. After the completion of the reaction, the reaction mixture was poured into water and neutralized with acetic acid. The precipitated crystals were recrystallized from ethyl acetate to give 0.21 g of 1-(3-cyano-4-(2-ethylbutoxy)phenyl)pyrazole-4-carboxylic acid, melting point 180-182° C.

Provenance & Evidence