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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 850084Generated: October 31, 2026

t-Butyl bromide → Ethyl 1-(4-tert-butoxy-3-cyanophenyl)pyrazole-4-carboxylate

https://huagongshe.com/reaction/850084

Reaction equation

Participants

RoleNameHCIDCharge
Reactantt-Butyl bromideHCID 10485—
ReactantEthyl 1-(3-cyano-4-hydroxyphenyl)pyrazole-4-carboxylateHCID 15407383—
ProductEthyl 1-(4-tert-butoxy-3-cyanophenyl)pyrazole-4-carboxylateHCID 19366018—

Reaction Steps

The same reaction and treatment as in Example 5 using ethyl 1-(3cyano-4-hydroxyphenyl)pyrazole-4-carboxylate and 1-bromo-1,1-dimethylethane gives ethyl 1-(4-tert-butoxy-3-cyanophenyl)pyrazole-4-carboxylate.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06015829
Source datasetuspto-grants-2000_01
ORD IDord-3c4054984a5346f1a01ec90694c2ce79
Source noteuspto-grants-2000_01