Water → (2,6-Dimethyl-3-nitrophenyl)methanol

HRID 850173Notes

Reaction equation

HRID 850173 reaction equation
C([O:4][CH2:5][C:6]1[C:11]([CH3:12])=[CH:10][CH:9]=[C:8]([N+:13]([O-:15])=[O:14])[C:7]=1[CH3:16])(=O)C.[OH-].[Na+].O>CO>[CH3:16][C:7]1[C:8]([N+:13]([O-:15])=[O:14])=[CH:9][CH:10]=[C:11]([CH3:12])[C:6]=1[CH2:5][OH:4]

Participants

5

Reactant 3

HCID 962WaterHCID 14798Sodium HydroxideHCID 10537042(2,6-Dimethyl-3-nitrophenyl)methyl acetate

Product 1

HCID 10487641(2,6-Dimethyl-3-nitrophenyl)methanolYield 82.4%

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

To a solution of 2,6-dimethyl-3-nitrobenzyl acetate (26.9 g) in methanol (266 ml) was added aqueous 1N sodium hydroxide solution (133 ml) at ambient temperature for 30 minutes. To the mixture was added water, and the precipitate was collected by filtration to give 2,6-dimethyl-3-nitrobenzyl alcohol (18.0 g) as pale yellow crystals.

Workup

  1. filtrationthe precipitate was collected by filtration

Sources & evidence

ORD record
ord-e5e5587fbd4a4698a1d3af9fb31aad28
Source dataset
uspto-grants-2000_01
Patent number
US06015818

Reaction notes

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