Methylcyclohexane → 4-Methoxycyclohexanone

HRID 850207Notes

Reaction equation

[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([OH:9])=[CH:5][CH:4]=1.CC1CCCCC1>>[CH3:1][O:2][CH:3]1[CH2:8][CH2:7][C:6](=[O:9])[CH2:5][CH2:4]1

Participants

Reactant 2

HCID 7962Methylcyclohexane

HCID 90154-Methoxyphenol2×

Product 1

HCID 5350284-Methoxycyclohexanone

Procedure

The procedure of Example I was repeated, but the p-methoxyphenol was used in molten form without addition of methylcyclohexane. After a hydrogenation time of 380 minutes, 62.1% by weight of the p-methoxyphenol had reacted and p-methoxycyclohexanone had been formed in a yield of 46.5% by weight.

Sources & evidence

ORD record: ord-5089a0d0ed914ee5a189d9f7a7a38812
Source dataset: uspto-grants-2000_01
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06015927

Reaction notes

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