1-([1,1'-Biphenyl]-4-yl)-N-methylmethanamine → HCID 86755085, compound

HRID 850212Notes

Reaction equation

HRID 850212 reaction equation
CNCC1C=CC(C2C=CC=CC=2)=CC=1.[CH3:16][C:17]([CH3:39])([CH3:38])[C:18]#[C:19]/[CH:20]=[CH:21]/[CH2:22][N:23]([CH2:25][C:26]1[CH:31]=[CH:30][C:29]([C:32]2[CH:37]=[CH:36][CH:35]=[CH:34][CH:33]=2)=[CH:28][CH:27]=1)[CH3:24]>>[CH3:16][C:17]([CH3:39])([CH3:38])[C:18]#[C:19]/[CH:20]=[CH:21]\[CH2:22][N:23]([CH2:25][C:26]1[CH:27]=[CH:28][C:29]([C:32]2[CH:37]=[CH:36][CH:35]=[CH:34][CH:33]=2)=[CH:30][CH:31]=1)[CH3:24]

Participants

3

Reactant 2

HCID 47223691-([1,1'-Biphenyl]-4-yl)-N-methylmethanamineHCID 9883462HCID 9883462, compound2×

Product 1

HCID 86755085HCID 86755085, compound

Procedure

N-methyl-4-phenylbenzylamine (0.75 g) was processed in a similar manner as in Synthesis Example 5, whereby trans-N-(6,6-dimethyl-2-hepten-4-yn-1-yl)-N-methyl-4-phenylbenzylamine (Compound 9) and cis-N-(6,6-dimethyl-2-hepten-4-yn-1-yl)-N-methyl-4-phenylbenzylamine (Compound 10) were obtained in amounts of 0.52 g (yield: 45%) and 0.12 g (yield: 10.4%), respectively. The followings are their NMR spectrum data:

Sources & evidence

ORD record
ord-5847bdecf415429180cefe607d7c0467
Source dataset
uspto-grants-2000_01
Patent number
US06015925

Reaction notes

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