Carbon tetrabromide → HCID 131721609, compound

Participants

Reaction Steps

To a solution of 26 mmol of 2-fluoro-4-dimethylbutylsilyloxy benzaldehyde in 50 ml of methylene chloride were added dropwise under ice-cooling 110 mmol of triphenyl phosphine and 52 mmol of carbon tetrabromide and the solution was stirred at the same temperature for one hour. The insoluble matter was removed from the reaction solution which was concentrated under reduced pressure to provide a yellow oily product. Purification of the product by a silica gel column chromatography gave 26 mmol of 2-fluoro-4-dimethylbutylsilyloxyphenyl-2,2-dibromoethylene as a colourless oily product.

Provenance & Evidence