N-bromobutanimide → Ethyl 2-bromo-(3,5-di-t-butyl-4-hydroxyphenyl)-acetate

Participants

Reaction Conditions

Reaction Steps

In carbon tetrachloride (15 mL) was dissolved Intermediate 10 (1.46 g, 5.0 mmol) and NBS (1.33 g, 7.5 mmol). The solution was treated with benzoyl peroxide (~2 mg) and warmed to 60° C. and stirred for 18 hours. The mixture was cooled to room temperature and filtered free of insolubles. The filtrate was evaporated in vacuo to give 2.0 g (>100%) of the crude product as an oil.

Provenance & Evidence