反应详情

温度

40 °C

In benzene (150 mL) was dissolved Intermediate 10 (6.7 g, 22.9 mmol) and this treated with a solution of potassium hydroxide (13.9 g [85%], 210 mmol) and potasium ferricyanide (K3Fe(CN)6) (15.2 g, 46 mmol) in water (150 mL). The mixture stirred under nitrogen atmosphere at 40° C. for 2 hours. The benzene layer then separated, washed with brine (100 mL) and dried over magnesium sulfate. The solvent was evaporated in vacuo to give a red oil, 6.1 g (92%), which was used as is.

1. customThe benzene layer then separated
2. washwashed with brine (100 mL)
3. dry with materialdried over magnesium sulfate
4. customThe solvent was evaporated in vacuo
5. customto give a red oil, 6.1 g (92%), which