HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 563266, compound → o-Tyramine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 563266 | HCID 563266 | — |
| Reactant | HCID 178418361 | HCID 178418361 | — |
| Catalyst | HCID 178418390 | HCID 178418390 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | o-Tyramine | HCID 74865 | 91.8% |
Reaction Steps
10% Palladium-carbon catalyst (water content 50%, 42 mg) was added to a solution of 2-(2-benzyloxyphenyl)ethylamine (415 mg, 1.826 mmol, 1.0 eq) in THF (10 ml), and the mixture was stirred for 2 hours at room temperature in a stream of hydrogen. The reaction mixture was filtered through Celite, and the filtrate was concentrated under reduced pressure to give 2-(2-hydroxyphenyl)ethylamine (230 mg, 91.8%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06017919 |
| Source dataset | uspto-grants-2000_01 |
| ORD ID | ord-456c83b17f7b4826b872e24c96a0cd6e |
| Source note | uspto-grants-2000_01 |