HCID 19363214, compound → HCID 19363422, compound

Participants

Reaction Steps

4-Methoxy-2-nitro-3-pentyloxybenzoic acid (26.8 g, 94.6 mmol) and ethanol (350 ml) were mixed, and 10% palladium-carbon catalyst (2.6 g) was added to this solution. The reaction miture was stirred at room temperature for 7.5 hours in a hydrogen gas stream (3 kgf/cm2) and filtered. The filtrate was concentrated under reduced pressure, and the precipitated crystals were collected by filtration to give 2-amino-4-methoxy-3-pentyloxybenzoic acid (22.7 g, 95%) as gray crystals.

Provenance & Evidence