HCID 19364484, compound → HCID 69720525, compound

HRID 850656Notes

Reaction equation

HRID 850656 reaction equation
[OH:1][CH:2]([C:18](=[O:58])[N:19]([CH:31]([CH3:57])[CH:32]([C:48]1[CH:53]=[CH:52][C:51]([N+:54]([O-:56])=[O:55])=[CH:50][CH:49]=1)[CH2:33][C:34]1[O:35][C:36]([C:39](=[O:47])[NH:40][C:41]2[CH:46]=[CH:45][CH:44]=[CH:43][CH:42]=2)=[CH:37][CH:38]=1)[CH2:20][C:21]1[CH:30]=[CH:29][C:28]2[C:23](=[CH:24][CH:25]=[CH:26][CH:27]=2)[CH:22]=1)[CH:3]([C:12]([O:14][CH:15]([CH3:17])[CH3:16])=[O:13])[CH2:4][CH2:5][C:6]([O:8]C(C)C)=[O:7].C(OC(C(=C(O)C(=O)N(C(C)C(C1C=CC([N+]([O-])=O)=CC=1)CC1OC(C(=O)NC2C=CC=CC=2)=CC=1)CC1C=CC2C(=CC=CC=2)C=1)CC(O)=O)=O)(C)(C)C>>[OH:1][C:2]([C:18](=[O:58])[N:19]([CH:31]([CH3:57])[CH:32]([C:48]1[CH:53]=[CH:52][C:51]([N+:54]([O-:56])=[O:55])=[CH:50][CH:49]=1)[CH2:33][C:34]1[O:35][C:36]([C:39](=[O:47])[NH:40][C:41]2[CH:42]=[CH:43][CH:44]=[CH:45][CH:46]=2)=[CH:37][CH:38]=1)[CH2:20][C:21]1[CH:30]=[CH:29][C:28]2[C:23](=[CH:24][CH:25]=[CH:26][CH:27]=2)[CH:22]=1)=[C:3]([C:12]([O:14][CH:15]([CH3:17])[CH3:16])=[O:13])[CH2:4][CH2:5][C:6]([OH:8])=[O:7]

Participants

3

Reactant 2

HCID 19364484HCID 19364484, compoundHCID 69721682HCID 69721682, compound

Product 1

HCID 69720525HCID 69720525, compound

Procedure

Isopropyl 5-hydroxy-4-isopropoxycarbonyl-5-[N-[(1RS,2RS)-1-methyl-2-(4-nitrophenyl)-3-{5-(phenylcarbamoyl)-2-furyl}propyl]-N-(2-naphthylmethyl)carbamoyl]pentanoate was treated in the same manner as in Example 25(2) and (3) to obtain the above-identified compound as a colorless oily substance.

Workup

  1. customto obtain the above-identified compound as a colorless oily substance

Sources & evidence

ORD record
ord-cb3229d5f4fc42c981a38f6c0122a72c
Source dataset
uspto-grants-2000_01
Patent number
US06017956

Reaction notes

Loading…