Oxygen → Gluconic Acid

HRID 850692Notes

Reaction equation

HRID 850692 reaction equation
[CH2:1]([OH:12])[C@H:2]1[O:8][C:6](=[O:7])[C@H:5]([OH:9])[C@@H:4]([OH:10])[C@@H:3]1[OH:11].[OH-].[Na+].O=O.C(=O)([O-])[O-:18].[Na+].[Na+]>O>[O:7]=[C:6]([OH:8])[C@@H:5]([C@H:4]([C@@H:3]([C@@H:2]([CH2:1][OH:12])[OH:18])[OH:11])[OH:10])[OH:9]

Participants

6

Reactant 4

HCID 977Oxygen3×HCID 7027delta-GluconolactoneHCID 10340Sodium CarbonateHCID 14798Sodium Hydroxide

Product 1

HCID 10690Gluconic Acid

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

50.0 g of gluconolactone is dissolved in 950 ml demineralised water. The pH is adjusted to 6.0 with 25 g of a 45% wiw sodium hydroxide solution.The solution is heated to 55° C. under nitrogen, until no more oxygen is detected. 6.35 g of the prepared Pb/Pt/C catalyst (ratio Pt/Pb 5/2) is added and the suspension is stirred at 1300 rpm for another 10 minutes under nitrogen. The reaction is started by switching from nitrogen to oxygen (maximum 10% oxygen in the mixture). The pH is kept at 6.0 by controlled addition of 26 ml 0.4 M sodium carbonate. The reaction is stopped after 1.5 hours reaction time reaching a selectivity of 89.9%.

Workup

  1. waitThe reaction is stopped after 1.5 hours
  2. customreaction time

Sources & evidence

ORD record
ord-4cc424c06190448ca945a0b82f1f290b
Source dataset
uspto-grants-2000_01
Patent number
US06018034

Reaction notes

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