Water → (2S,4S)-4,5-dihydroxynorvaline

HRID 850703Notes

Reaction equation

HRID 850703 reaction equation
[CH2:1]1[C@@H:5]([C:6]([OH:8])=[O:7])[NH:4][CH2:3][C@H:2]1[OH:9].[OH2:10]>>[OH:9][C@H:2]([CH2:3][OH:10])[CH2:1][C@@H:5]([C:6]([OH:8])=[O:7])[NH2:4]

Participants

3

Reactant 2

HCID 962WaterHCID 440015Cis-4-Hydroxy-L-Proline

Product 1

HCID 11194422(2S,4S)-4,5-dihydroxynorvaline

Procedure

[α]D21 =-23.9 (c =1.0, water) Further reactions analogously to J. Am. Chem. Soc. 1986, 108, 6041 lead to L-cis-4-hydroxyproline

Sources & evidence

ORD record
ord-8c259976a14b4df78569cb5cb5d09593
Source dataset
uspto-grants-2000_01
Patent number
US06018050

Reaction notes

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