HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(Dimethylaminomethyl)-4-(2-aminoethylthiomethyl)thiazole → HCID 178483318, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(Dimethylaminomethyl)-4-(2-aminoethylthiomethyl)thiazole | HCID 10977318 | — |
| Reactant | N-Nitro-S-methylisothiourea | HCID 135927615 | — |
| Product | HCID 178483318 | HCID 178483318 | — |
Reaction Steps
Following the above procedure, 2-(2-dimethylaminomethyl-4-thiazolylmethylthio)ethylamine was reacted with S-methyl N-nitroisothiourea to yield N-2-(2-dimethylaminomethyl-4-thiazolylmethylthio)ethyl-N'-nitroguanidine. The compound was purified by chromatography (silica-ethyl acetate/methanol), and melted at 104°-105.5° C. after recrystallization from ethyl acetate.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04382090 |
| Source dataset | uspto-grants-1983_05 |
| ORD ID | ord-28a43aa0751d4152801f4931a81eb7eb |
| Source note | uspto-grants-1983_05 |