Sodium Methoxide → 4-Dimethylsilylphenol

Participants

Reaction Steps

To a cold solution (~9° C.) of 26.0 g of 4-dimethylsilylphenoxydimethylsilane in 250 ml of diethylether was added 10 ml of a solution of sodium methoxide (0.4 N) in methanol and the mixture stirred overnight. Solvents were removed by evaporation on a rotary evaporator at room temperature to yield 15.6 g (83.0%) of crude product, m.p. 59°-60° C. After recrystallization from hexane, the phenol was obtained as needles, m.p. 61° C.

Provenance & Evidence