反应详情

To 1.1 g. of ethyl 5-hexadecanamido-2-thiophenecarboxylate is added 5 ml. 1 M borane in tetrahydrofuran. The reaction mixture is refluxed for 1 hour. After cooling, the reaction mixture is poured into 50 ml. of 1 N hydrochloric acid. The solid is collected and then recrystallized from both carbon tetrachloride and ethanol to yield the product.

1. temperatureThe reaction mixture is refluxed for 1 hour
2. temperatureAfter cooling
3. additionthe reaction mixture is poured into 50 ml
4. customThe solid is collected
5. customrecrystallized from both carbon tetrachloride and ethanol
6. customto yield the product