反应详情

A mixture of 2.0 g. of ethyl 5-hexadecylamino-2-furancarboxylate, 10 ml. of ethanol, and 2.0 ml. of 1 N sodium hydroxide is stirred under reflux for 3 hours and then allowed to cool. The mixture is concentrated in vacuo, diluted with water, and adjusted to pH 5 with the dropwise addition of dilute hydrochloric acid. The solid is collected by filtration, washed with water, and dried to yield the product.

1. additionA mixture of 2.0 g
2. temperatureunder reflux for 3 hours
3. temperatureto cool
4. concentrationThe mixture is concentrated in vacuo
5. additiondiluted with water
6. additionadjusted to pH 5 with the dropwise addition of dilute hydrochloric acid
7. filtrationThe solid is collected by filtration
8. washwashed with water
9. customdried
10. customto yield the product