Sulfuric Acid → HCID 20503613, compound

Participants

Reaction Steps

A mixture of 1.0 g. of ethyl 4-hexadecylamino-1-methyl-2-pyrrolecarboxylate and 10 ml. of 40% aqueous sulfuric acid is heated under reflux for 24 hours, allowed to cool and neutralized with sodium acetate. The mixture is extracted with chloroform and the extract is dried over magnesium sulfate and evaporated. The residue is purified by chromatography on a silica gel column by elution with chloroform-acetic acid mixtures. Evaporation of the eluate affords the product.

Provenance & Evidence