Sodium Cyanide → Cypermethrin

Participants

Reaction Steps

A 500 ml. round-bottomed flask equipped with a stirrer operating at 500 rpm was charged with 0.2 mole of 3-phenoxybenzaldehyde, 20 ml. of water, 15.2 g. of sodium cyanide, 90 ml. of cyclohexane and a catalyst (if any). 0.2 mole of 2-(2',2'-dichlorovinyl)-3,3-dimethylcyclopropanecarbonyl chloride was added at 15°-20° over 30 minutes, followed by 10 ml. of cyclohexane. The mixture thus formed was stirred at 15°-20° C. At the end of the reaction, 100 ml. of water were added and the organic phase was filtered, washed with 100 ml. of water and the cyclohexane was then removed on a rotary evaporator. The catalysts used and the results obtained are shown in Table 1.

Provenance & Evidence