Sulfuric Acid → Ethyl trifluoroacetate

HRID 851076Notes

Reaction equation

HRID 851076 reaction equation
B(Br)(Br)Br.[C:5]([C:9](Cl)(Cl)Cl)([F:8])([F:7])[F:6].[OH:13]S(O)(=O)=O.F[C:19](F)(F)[C:20](Cl)=[O:21]>C(O)C>[CH2:20]([O:21][C:9](=[O:13])[C:5]([F:8])([F:7])[F:6])[CH3:19]

Participants

6

Reactant 4

HCID 1118Sulfuric Acid2×HCID 96351,1,1-Trichloro-2,2,2-trifluoroethaneHCID 25134Boron tribromideHCID 61106Trifluoroacetyl chloride

Product 1

HCID 9794Ethyl trifluoroacetate

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

Into the experimental apparatus described in Example 1, 2 g HgSO4 and 10 g BBr3 are added. A solution of 93.7 g CF3CCl3, 162 g SO3 and 4 g H2SO4 are added in drops. The trifluoroacetylchloride leaving the reflux condenser is passed through a wash flask with H2SO4 and subsequently fed into a reaction vessel with ethanol. In the process, trifluoracetic acid ethylester is formed.

Workup

  1. additionare added

Sources & evidence

ORD record
ord-afd4b0d95c4d4605901b3fe03cd5eef6
Source dataset
uspto-grants-1983_05
Patent number
US04382897

Reaction notes

Loading…