HuagongsheHuagongshe Chemistry Print Report · For research reference only
L-Aspartic Acid → 7-(3-Aminopyrrolidin-1-yl)-1-ethenyl-6-fluoro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | L-Aspartic Acid | HCID 5960 | — |
| Reactant | 7-(3-Aminopyrrolidin-1-yl)-1-ethenyl-6-fluoro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid | HCID 3069215 | — |
| Solvent | Water | HCID 962 | — |
| Product | 7-(3-Aminopyrrolidin-1-yl)-1-ethenyl-6-fluoro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid | HCID 3069215 | — |
| Product | l-aspartic acid, sodium salt | HCID 5460541 | — |
Reaction Steps
An equimolar mixture of the compound 1 and L-aspartic acid was treated in water in a similar manner to give L-aspartate (as a mono-hydrate) of the compound 1, m.p. 235°-240° C. with decomposition.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04382937 |
| Source dataset | uspto-grants-1983_05 |
| ORD ID | ord-a578c60d0e9644358abf2045833d883b |
| Source note | uspto-grants-1983_05 |