Sodium borohydride → HCID 12599102, compound

HRID 851169Notes

Reaction equation

HRID 851169 reaction equation
[CH3:1][C:2]([CH3:10])([CH3:9])/[CH:3]=[CH:4]/[CH:5]=[CH:6]/[CH:7]=[O:8].[BH4-].[Na+]>C(O)C>[CH3:1][C:2]([CH3:10])([CH3:9])/[CH:3]=[CH:4]/[CH:5]=[CH:6]/[CH2:7][OH:8]

Participants

4

Reactant 2

HCID 4311764Sodium borohydrideHCID 10855526HCID 10855526, compound

Product 1

HCID 12599102HCID 12599102, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

2 g Trans,trans-6,6-dimethyl-2,4-heptadienal are dissolved in ethanol and reacted at room temperature with 275 mg NaBH4 in successive portions. After stirring for ca. 1 hour at room temperature the mixture is concentrated on a rotary evaporator, the residue partitioned between ethyl acetate and saturated aqueous NaHCO3 and the organic phase dried and concentrated under vacuum. The oily crude product is further reacted directly.

Workup

  1. concentrationis concentrated on a rotary evaporator
  2. customthe residue partitioned between ethyl acetate and saturated aqueous NaHCO3
  3. customthe organic phase dried
  4. concentrationconcentrated under vacuum
  5. customThe oily crude product is further reacted directly

Sources & evidence

ORD record
ord-4a4a230aa3ed43b9a6490d7361835e53
Source dataset
uspto-grants-1983_05
Patent number
US04382951

Reaction notes

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