Sodium Iodide → HCID 13079642, compound

Participants

Reaction Steps

To a suspension of 4-hydroxy-α,α-dimethylbenzenepropanol (15 g, 0.083 m) in water, was added a solution of sodium hydroxide (5 g, 0.125 m) in water (50 ml). 2-Bromoethanol (11.4 g, 0.091 m) and sodium iodide (6.3 g) were successively added and the solution stirred and heated under reflux for 3 hours. The reaction mixture was then diluted with more water and extracted with ethyl acetate. Evaporation of the ethyl acetate gave a cream solid (21.3 g).

Provenance & Evidence