1-Naphthol → HCID 13136910, compound

HRID 851187Notes

Reaction equation

HRID 851187 reaction equation
[C:1]1([OH:11])[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=[CH:3][CH:2]=1.Cl.O=[C:14]1[CH2:19][CH2:18][NH:17][CH2:16][CH:15]1[C:20](O)=[O:21]>>[CH2:16]1[C:15]2[C:20](=[O:21])[O:11][C:1]3[C:10]4[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=4)[CH:4]=[CH:3][C:2]=3[C:14]=2[CH2:19][CH2:18][NH:17]1

Participants

3

Reactant 2

HCID 70051-NaphtholHCID 13381780HCID 13381780, compound

Product 1

HCID 13136910HCID 13136910, compoundYield 29.4%

Procedure

Prepared by the method described in Example 1 from 1-napthol (10.0 g, 0.069 moles) and 4-oxo-3-piperidinecarboxylate hydrochloride (9.6 g, 0.05 moles). Recrystallization from 2-propanol/N,N-dimethylformamide yielded the product (3.7 g), mp 227°-230° C.

Workup

  1. customPrepared by the method
  2. customRecrystallization from 2-propanol/N,N-dimethylformamide

Sources & evidence

ORD record
ord-6eec5184ef1647428e1581cbe2c0c276
Source dataset
uspto-grants-1983_05
Patent number
US04382939

Reaction notes

Loading…