HuagongsheHuagongshe Chemistry Print Report · For research reference only
3,4-Dimethoxyphenol → HCID 10825289, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3,4-Dimethoxyphenol | HCID 16251 | — |
| Reactant | 3-Piperidinecarboxylic acid, 4-oxo-, ethyl ester, hydrochloride (1:1) | HCID 107315 | — |
| Solvent | Sulfuric Acid | HCID 1118 | — |
| Product | HCID 10825289 | HCID 10825289 | 75.5% |
Reaction Steps
Prepared by the method described in Example 1 except that the 3,4-dimethoxyphenol (61.5 g, 0.40 moles) is added in one portion to an ice-cooled mixture of ethyl 4-oxo-3-piperidinecarboxylate hydrochloride (75 g, 0.36 moles) and 200 ml of 72% sulfuric acid. Recrystallization from acetonitrile yielded the product (71 g), mp 186°-188° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04382939 |
| Source dataset | uspto-grants-1983_05 |
| ORD ID | ord-846a71034a5f43e7961b9b06209e78a8 |
| Source note | uspto-grants-1983_05 |