HCID 20501879, compound → HCID 178449187, compound

HRID 851274Notes

Reaction equation

HRID 851274 reaction equation
[C:1]([NH:5][C:6]([NH:8][C:9]1[CH:10]=[N:11][CH:12]=[CH:13][CH:14]=1)=S)([CH3:4])([CH3:3])[CH3:2].[N:15]#[C:16][NH2:17].[Pb]>C(O)C>[C:1]([NH:5][C:6]([NH:8][C:9]1[CH:10]=[N:11][CH:12]=[CH:13][CH:14]=1)=[N:17][C:16]#[N:15])([CH3:4])([CH3:3])[CH3:2]

Participants

4

Reactant 2

HCID 20501879HCID 20501879, compoundHCID 22262466CH2N2Pb

Product 1

HCID 178449187HCID 178449187, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

N-tert-butyl-N'-3-pyridylthiourea (2.1 g) and lead cyanamide (3.7 g) were refluxed in ethanol (20 ml) for 18 hours. The mixture was filtered, and the filtrate was evaporated in vacuo to afford the crude product. Recrystallization from aqueous acetone gave the desired compound. Melting point 205.0°-206.5° C.

Workup

  1. filtrationThe mixture was filtered
  2. customthe filtrate was evaporated in vacuo
  3. customto afford the crude product
  4. customRecrystallization from aqueous acetone

Sources & evidence

ORD record
ord-443601a1e26d4193812884f46191c1fe
Source dataset
uspto-grants-1983_05
Patent number
USRE031244

Reaction notes

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