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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 85131Generated: October 26, 2026

2-Amino-thiazole-5-carboxylic acid ethyl ester → 5-(Morpholinomethyl)thiazol-2-amine

https://huagongshe.com/reaction/85131

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Amino-thiazole-5-carboxylic acid ethyl esterHCID 314628—
Reactant4-(Morpholin-4-ylmethyl)-1,3-thiazol-2-amineHCID 2125344—
Product5-(Morpholinomethyl)thiazol-2-amineHCID 21525106—

Reaction Steps

5-(morpholinomethyl)thiazol-2-amine 61 was prepared using the same synthetic sequence outlined above for 4-(morpholinomethyl)thiazol-2-amine employing ethyl 2-aminothiazole-5-carboxylate 60 as the starting material.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08846947B2
Source datasetuspto-grants-2014_09
ORD IDord-9e42ffb378d34c269b57ed97622cfe2f
Source noteuspto-grants-2014_09