Dimethyl Sulfide → HCID 54280359, compound

Participants

Reaction Conditions

Reaction Steps

A solution of methyl [(4R)-2-oxo-4-(1,2,4-trioxolan-3-ylmethyl)azetidin-1-yl]glyoxylate (320 mg) and dimethyl sulfide (2 ml) in a mixture of dichloromethane (9 ml) and methanol (10 ml) was stirred at 5° C. for 6 hours and at room temperature for 15 hours. The mixture was then heated at 50° for 4 hours and evaporated to give methyl [(4R)-2-oxo-4-(2-oxoethyl)-azetidin-1-yl]glyoxylate.

Provenance & Evidence