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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 851496Generated: October 26, 2026

Sodium ethoxide → 2-[2-(4-Dimethylaminomethyl-2-pyridylmethylthio)ethylamino]-5-(6-methyl-3-pyridylmethyl)-4-pyrimidone

https://huagongshe.com/reaction/851496

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSodium ethoxideHCID 2723922—
ReactantHCID 20239077HCID 20239077—
ReactantHCID 178483283HCID 178483283—
SolventEthanolHCID 702—
Product2-[2-(4-Dimethylaminomethyl-2-pyridylmethylthio)ethylamino]-5-(6-methyl-3-pyridylmethyl)-4-pyrimidoneHCID 13292604—

Reaction Steps

Reaction of N-[2-(4-dimethylaminomethyl-2-pyridylmethylthio)ethyl]guanidine hemisulphate with ethyl 2-formyl-3-(6-methyl-3-pyridylmethyl)propionate and sodium ethoxide in ethanol gives 2-[2-(4-dimethylaminomethyl-2-pyridyl-methylthio)ethylamino]-5-(6-methyl-3-pyridylmethyl)-4-pyrimidone.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04385058
Source datasetuspto-grants-1983_05
ORD IDord-459fc672ce8e4fca82ffcca6827410d2
Source noteuspto-grants-1983_05