HCID 20456433, compound → Dicyclohexylamine

HRID 851552Notes

Reaction equation

HRID 851552 reaction equation
Cl[C:2]1(OC)[CH:10]=[CH:9][C:8]2[N:7]([C:11](=O)[C:12]([CH3:14])=C)C(C(O)=O)C[C:4]=2[CH2:3]1.[C:21](SCC(C)C(N1C2C(=CC(Cl)=CC=2)CC1C(O)=O)=O)(=O)[C:22]1C=CC=C[CH:23]=1>>[CH:11]1([NH:7][CH:8]2[CH2:4][CH2:3][CH2:2][CH2:10][CH2:9]2)[CH2:12][CH2:14][CH2:23][CH2:22][CH2:21]1

Participants

3

Reactant 2

HCID 20456433HCID 20456433, compoundHCID 70531547HCID 70531547, compound

Product 1

HCID 7582Dicyclohexylamine

Procedure

By substituting 5-chloro-2,3-dihydro-5-methoxy-1-(2-methyl-1-oxo-2-propenyl)-1H-indole-2-carboxylic acid in the procedure of Example 25, 1-[3-(benzoylthio)-2-methyl-1-oxopropyl]-5-chloro-2,3dihydro-1H-indole-2-carboxylic acid, dicyclohexylamine was obtained. The latter salt was then treated with 5% aqueous potassium hydrogen sulfate as in Example 15 to give the titled compound.

Sources & evidence

ORD record
ord-3a9e6d825703444e94a82eafb0844bc8
Source dataset
uspto-grants-1983_05
Patent number
US04385180

Reaction notes

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