p-Toluidine → HCID 13442302, compound

Participants

Reaction Steps

2 kg (8.4 mols) of 3,5-dinitrophthalic anhydride and 897 g (8.4 mols) of p-toluidine in 6.2 l of glacial acetic acid are kept under reflux for 3 hours. After cooling, the mixture is filtered, the residue is rinsed with 2 l of water and then suspended in 25 l of water, and the product is filtered off and dried at 100° C. in vacuo. 2,339 g (85% of theory) of N-(p-toluyl)-3,5-dinitrophthalimide are obtained; melting point: 182°-3° C.

Provenance & Evidence