Sodium Hydroxide → 8-[4-Methoxy-N-(4-methoxyphenyl)-benzamido]-caprylic acid

HRID 851651Notes

Reaction equation

HRID 851651 reaction equation
C[O:2][C:3](=[O:30])[CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][N:11]([C:22]1[CH:27]=[CH:26][C:25]([O:28][CH3:29])=[CH:24][CH:23]=1)[C:12](=[O:21])[C:13]1[CH:18]=[CH:17][C:16]([O:19][CH3:20])=[CH:15][CH:14]=1.[OH-].[Na+]>CO>[CH3:20][O:19][C:16]1[CH:17]=[CH:18][C:13]([C:12]([N:11]([CH2:10][CH2:9][CH2:8][CH2:7][CH2:6][CH2:5][CH2:4][C:3]([OH:30])=[O:2])[C:22]2[CH:27]=[CH:26][C:25]([O:28][CH3:29])=[CH:24][CH:23]=2)=[O:21])=[CH:14][CH:15]=1

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 538841738-[4-Methoxy-N-(4-methoxyphenyl)-benzamido]-caprylic acid methyl ester

Product 1

HCID 205007918-[4-Methoxy-N-(4-methoxyphenyl)-benzamido]-caprylic acid

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

As described in example 1(b), 10 g (24 mmol) of 8-[4-methoxy-N-(4-methoxyphenyl)-benzamido]-caprylic acid methyl ester is reacted with 2 g (50 mmol) of sodium hydroxide and 200 cc. of methanol. Reaction time: 6 hours, reaction temperature: 25° C.

Workup

  1. customReaction time
  2. custom6 hours, reaction temperature
  3. custom25° C.

Sources & evidence

ORD record
ord-32d784c0681a4cbbacd3c1b8af830da5
Source dataset
uspto-grants-1983_05
Patent number
US04386031

Reaction notes

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