HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Iodide → 11-[4-Chloro-N-(4-methoxyphenyl)-benzamido]-undecanoic acid methyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Iodide | HCID 5238 | — |
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | 4-Chloro-N-(4-methoxyphenyl)benzamide | HCID 221848 | — |
| Reactant | Methyl 11-bromoundecanoate | HCID 223913 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 11-[4-Chloro-N-(4-methoxyphenyl)-benzamido]-undecanoic acid methyl ester | HCID 53768777 | — |
Reaction Steps
As described in example 1(a), the reaction is carried out with 28.7 g (0.11 mol) of 4-chloro-N-(4-methoxyphenyl)-benzamide, 4.5 g (0.18 mol) of sodium hydride, 36.7 g (0.13 mol) of 11-bromoundecanoic acid methyl ester, 100 cc. of dimethylformamide and 3 g (0.02 mol) of sodium iodide. Reaction time: 5 hours, reaction temperature: 80° C. The crude product is used in the next step without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04386031 |
| Source dataset | uspto-grants-1983_05 |
| ORD ID | ord-2bbc21696e9d4ecea78e99c5f72b5e1d |
| Source note | uspto-grants-1983_05 |