Triethyl phosphite → Phosphinecarboxylic acid, diethoxy-, 4-chlorophenyl ester, oxide

HRID 851698Notes

Reaction equation

HRID 851698 reaction equation
C([O:3][P:4]([O:8][CH2:9][CH3:10])[O:5][CH2:6][CH3:7])C.Cl[C:12]([O:14][C:15]1[CH:20]=[CH:19][C:18]([Cl:21])=[CH:17][CH:16]=1)=[O:13]>>[Cl:21][C:18]1[CH:19]=[CH:20][C:15]([O:14][C:12]([P:4](=[O:3])([O:5][CH2:6][CH3:7])[O:8][CH2:9][CH3:10])=[O:13])=[CH:16][CH:17]=1

Participants

3

Reactant 2

HCID 31215Triethyl phosphiteHCID 1390594-Chlorophenyl chloroformate

Product 1

HCID 512115Phosphinecarboxylic acid, diethoxy-, 4-chlorophenyl ester, oxide

Procedure

From 20 g (0.12 mole) of triethylphosphite and 19.1 g (0.10 mole) of 4-chlorophenyl chloroformate (prepared according to M. J. Zabik and R. D. Scheutz J. Org. Chem. 32 (1967) 300). (125° C., 2 hours). Yield 26.3 g (90%). Bp0.01 153°-6° C., nD21 1.4980.

Workup

  1. custom(125° C., 2 hours)
  2. customBp0.01 153°-6° C.

Sources & evidence

ORD record
ord-0c1e05a547334a8c81d0574c35b4131c
Source dataset
uspto-grants-1983_05
Patent number
US04386081

Reaction notes

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