Dimethyl Sulfoxide → HCID 53725896, compound

Participants

Reaction Steps

11.35 g (0.03 mole) of 2-(2-methyl-3-phenylsulfonyl-prop-1-yl)-cyclododecanone and 11.0 g (0.197 mole) of powdered KOH in 30 ml of toluene were first heated to reflux during 30 min., in a reaction vessel fitted with a water separator. After addition of 6 ml of DMSO, the reaction mixture was further heated at 110°, for 12 hours. After the treatments of extraction, washing, drying and distillation (0.05 Torr--bath temperature: 150°) described in Example 1, there were isolated 5.61 g (86% yield) of the desired compound.

Provenance & Evidence