Thiophenol → HCID 53725896, compound

Participants

Reaction Steps

2-(2-Methyl-3-phenylsulfonyl-prop-1-yl)-cyclododecanone used hereinabove (Examples 3 and 4) as starting material was prepared as follows: 235 g (1 mole) of 2-methallyl-cyclododecanone--Chem. Comm. 1976, 1021--in admixture with 132 g (1.2 mole) of thiophenol and 3.0 g (0.018 mole) of α,α'-azoisobutyronitrile were heated at 115° for 32 hours and subsequently subjected to oxidation in accordance with the method described in Example 2 for 2-(3-phenylsulfonyl-prop-1-yl)-cyclododecanone to afford, after the above mentioned treatments of extraction and purification, 325 g (86% yield) of the desired compound, m.p. 98°-103°.

Provenance & Evidence