2-Methylbenzimidazole → HCID 58927102, compound

HRID 851846Notes

Reaction equation

[CH3:1][C:2]1[NH:3][C:4]2[CH:10]=[CH:9][CH:8]=[CH:7][C:5]=2[N:6]=1.[CH2:11]([O:13][CH2:14][CH2:15][O:16][CH2:17][CH2:18]Cl)[CH3:12]>>[CH2:11]([O:13][CH2:14][CH2:15][O:16][CH2:17][CH2:18][N:3]1[C:4]2[CH:10]=[CH:9][CH:8]=[CH:7][C:5]=2[N:6]=[C:2]1[CH3:1])[CH3:12]

Participants

Reactant 2

HCID 119842-Methylbenzimidazole

HCID 170577Ethane, 1-(2-chloroethoxy)-2-ethoxy-

Product 1

HCID 58927102HCID 58927102, compoundYield 84%

Procedure

1-[2-(2-Ethoxyethoxy)ethyl]-2-methyl-1H-benzimidazole was synthesized as in Synthesis Example 1 except that an equimolar amount of 2-methylbenzimidazole was used instead of benzimidazole and an equimolar amount of 2-chloroethyl 2-ethoxyethyl ether was used instead of 2-chloroethyl methyl ether. Yield 84%.

Sources & evidence

ORD record: ord-fa4eb3e3bd144c348f571738440cde91
Source dataset: uspto-grants-2007_08
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07252925B2

Reaction notes

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