Lawesson's reagent → HCID 23023848, compound

Participants

Reaction Steps

A solution of 3-cyano-4-isobutyloxy-N-(3-methoxyphenyl)benzamide (972 mg, 3.0 mmol) and Lawesson's reagent (808 mg, 2.0 mmol) in toluene (5 mL) was heated under reflux for 3.5 hours. After addition of toluene (approx. 20 mL), the heated solution was allowed overnight to lapse at room temperature. The precipitated crystalline product was collected by filtration, to give 900 mg (yield 88%) of the desired compound in the form of a yellow crystalline product.

Provenance & Evidence