HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 852018Generated: October 27, 2026
Acetic Acid → 4,6-Dichloro-2-(methylthio)-5-pyrimidinecarbaldehyde oxime
https://huagongshe.com/reaction/852018
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Acetic Acid | HCID 176 | — |
| Reactant | Hydroxyamine hydrochloride | HCID 443297 | — |
| Reactant | 4,6-Dichloro-2-(methylsulfanyl)pyrimidine-5-carbaldehyde | HCID 4614004 | — |
| Solvent | Water | HCID 962 | — |
| Product | 4,6-Dichloro-2-(methylthio)-5-pyrimidinecarbaldehyde oxime | HCID 21822251 | — |
Reaction Steps
4,6-Dichloro-2-methylsulfanyl-pyrimidine-5-carbaldehyde (7.34 g, 33.09 mmol), hydroxylamine hydrochloride (2.31 g, 33.33 mmol), acetic acid (49.6 mL), and water (3.3 mL) were mixed, and heated to 60° C. for 2 hours. The reaction mixture was diluted with water and cooled under ice bath. The precipitate was collected and dried (Yield=6.41 g, 82%). MS (m/z): 238 (M+H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US07253174B2 |
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| Source dataset | uspto-grants-2007_08 |
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| ORD ID | ord-0df1b534df074f86942cf962850a2f9d |
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| Source note | uspto-grants-2007_08 |
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