反应详情

To a solution of N-(2,2-dimethyl-propyl)-N-methyl-N′-[2-methyl-5-(4H-[1,2,4]triazol-3-yl)phenyl]-5-nitro-pyrimidine-4,6-diamine (20 mg, 0.05 mmol) in 5 mL of methanol was added a catalytic amount of 10% Pd/C. The vessel was placed under a hydrogen atmosphere of 20 psi for 1 h at room temperature. The solution was filtered, and the filtrate was evaporated under vacuum to afford 4.6 mg of the product (Yield: 25%). MS (m/z) calcd for C19H26N8 (MH+), 367.2, found, 367.4.

1. filtrationThe solution was filtered
2. customthe filtrate was evaporated under vacuum