反应详情

A suspension of [2-(benzyloxy)-4-pyridyl]methanol (6.0 g) and activated manganese dioxide (30 g) in chloroform (180 mL) was heated under reflux for 2.5 hours. After the reaction solution was allowed to cool to room temperature, the manganese dioxide was filtered off and washed with ethyl acetate. The filtrate was concentrated to give the title compound as a pale brown oil (5.34 g).

1. temperaturewas heated
2. temperatureunder reflux for 2.5 hours
3. filtrationthe manganese dioxide was filtered off
4. washwashed with ethyl acetate
5. concentrationThe filtrate was concentrated