反应详情

Combine (2-chloro-pyridin-3-yl)-(3-methoxy-phenyl)-methanol (9.40 g, 37.6 mmol), manganese (IV) oxide (30.0 g, 0.345 mol) and toluene (500 mL) and heat to reflux for one hour. Filter reaction mixture through celite, wash with toluene:dichloromethane mixture and evaporate to give the title compound (1.63 g, 66% Yield).

1. temperatureto reflux for one hour
2. filtrationFilter
3. customreaction mixture through celite
4. washwash with toluene
5. customdichloromethane mixture and evaporate