Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 852118Generated: October 31, 2026

(S)-(+)-2-(Methoxymethyl)pyrrolidine → HCID 58928313, compound

https://huagongshe.com/reaction/852118

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(S)-(+)-2-(Methoxymethyl)pyrrolidineHCID 671217—
Reactant(R)-6-fluoro-3-(4-oxiranylmethoxy-phenyl)-benzo[d]isoxazoleHCID 58928269—
SolventEthanolHCID 702—
SolventDimethylformamideHCID 6228—
ProductHCID 58928313HCID 58928313—

Reaction Steps

The title compound is prepared from a mixture of (R)-6-fluoro-3-(4-oxiranylmethoxy-phenyl)-benzo[d]isoxazole in dimethylformamide and (S)-(+)-2-(methoxymethyl)pyrrolidine in ethanol essentially as described above in Example 21. Purity by LC/MS=100%, [M+H]+=401.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07253165B2
Source datasetuspto-grants-2007_08
ORD IDord-3eddc1e152bb4df5ab4129a3d8a2af56
Source noteuspto-grants-2007_08