HuagongsheHuagongshe Chemistry Print Report · For research reference only
6-fluoro-3-piperazin-1-yl-1H-indazole → HCID 9849038, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6-fluoro-3-piperazin-1-yl-1H-indazole | HCID 9815871 | — |
| Reactant | (R)-6-fluoro-3-(4-oxiranylmethoxy-phenyl)-benzo[d]isoxazole | HCID 58928269 | — |
| Solvent | Ethanol | HCID 702 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 9849038 | HCID 9849038 | — |
Reaction Steps
The title compound is prepared from a mixture of (R)-6-fluoro-3-(4-oxiranylmethoxy-phenyl)-benzo[d]isoxazole in dimethylformamide and 6-fluoro-3-piperazin-1-yl-1H-indazole (Table No.1, SM 4) in ethanol essentially as described above in Example 21. Purity by LC/MS=100%, [M+H]+=506.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07253165B2 |
| Source dataset | uspto-grants-2007_08 |
| ORD ID | ord-41b0d19e2654403c86051d04e7b5c3a3 |
| Source note | uspto-grants-2007_08 |