HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Dimethylformamide → (S)-1-(cyclohexyl-methyl-amino)-3-[4-(6-fluoro-benzo[d]isoxazol-3-yl)-phenoxy]-propan-2-ol
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Dimethylformamide | HCID 6228 | — |
| Edukt | (S)-6-fluoro-3-(4-oxiranylmethoxy-phenyl)-benzo[d]isoxazole | HCID 11254641 | — |
| Lösungsmittel | Ethanol | HCID 702 | — |
| Lösungsmittel | N-Methylcyclohexylamine | HCID 7514 | — |
| Produkt | (S)-1-(cyclohexyl-methyl-amino)-3-[4-(6-fluoro-benzo[d]isoxazol-3-yl)-phenoxy]-propan-2-ol | HCID 9865612 | — |
Reaktionsschritte
The title compound is prepared from a mixture of (S)-6-fluoro-3-(4-oxiranylmethoxy-phenyl)-benzo[d]isoxazole in dimethylformamide and N-methylcyclohexylamine in ethanol essentially as described above in Example 21. Purity by LC/MS=100%, [M+H]+=399.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07253165B2 |
| Quelldatensatz | uspto-grants-2007_08 |
| ORD ID | ord-5a1efa3e0899489a80c9e223a57a8c87 |
| Quellennotiz | uspto-grants-2007_08 |