HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(2-Pyrimidinyl)piperazine → HCID 58928301, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(2-Pyrimidinyl)piperazine | HCID 88747 | — |
| Reactant | (R)-6-fluoro-3-(4-oxiranylmethoxy-phenyl)-benzo[d]isoxazole | HCID 58928269 | — |
| Solvent | Ethanol | HCID 702 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 58928301 | HCID 58928301 | — |
Reaction Steps
The title compound is prepared from a mixture of (R)-6-fluoro-3-(4-oxiranylmethoxy-phenyl)-benzo[d]isoxazole in dimethylformamide and 2-piperazin-1-yl-pyrimidine in ethanol, essentially as described above in Example 70. Purity by LC/MS=-100%, [M+H]+=450.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07253165B2 |
| Source dataset | uspto-grants-2007_08 |
| ORD ID | ord-25a3e5a71d8a4866892630faa22ba131 |
| Source note | uspto-grants-2007_08 |